In general, these drugs are not thought to possess the same sort of abuse potential as other classes of drugs discussed in this section. Mescaline and LSD are serotonin agonists, and PCP (angel dust) and ketamine (an animal anesthetic) act as antagonists of the NMDA glutamate receptor. autonomic nervous system side effects should be minimal andĪs a group, hallucinogens are incredibly varied in terms of the neurotransmitter systems they affect.stupor, narcosis, or excessive stimulation should not be an integral effect. intellectual or memory impairment should be minimal.in proportion to other effects, changes in thought, perception, and mood should predominate.Leo Hollister’s five criteria for establishing that a drug is hallucinogenic are as follows: These substances also commonly cause hallucinations of body sensations (e.g., feeling as if you are a giant) and a skewed perception of the passage of time. Common hallucinogens include psilocybin (shrooms), mescaline (peyote), and LSD. In some cases, users experience vivid visual hallucinations.
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